Modeling and investigating the behavior of triangular origami DNA under the influence of laboratory temperature

Document Type : Original Article

Authors
1 PhD candidate, Department of Mechanical Engineering, Ferdowsi University of Mashhad, Iran.
2 Associate Professor, Department of Mechanical Engineering, Hakim Sabzevari University, Iran.
Abstract
In this article, the mechanical behavior of triangular origami DNA, which has special appearance and functional characteristics, has been investigated. Triangular origami DNA can be introduced as a Nano-device with several degrees of freedom. To investigate this issue, molecular dynamics modeling and simulation have been done and then its performance is analyzed. The first step in knowing a Nano-device is its structural analysis. In this report, the structural changes of the Nano-device due to the change in temperature have been investigated the results show that the amount of structural changes has reached its lowest level in approximately 800 picoseconds. After this period of time, it can be said that the triangular origami DNA has relatively reached structural stability. The mechanical behavior of origami DNA will be such that it is suitable for taking different volumes of cargo. In other words, it can be used to carry Nano drugs with various dimensions. In fact, the most interesting parameter in this Nano-device is the flexibility of its arms. This flexibility can be properly used to carry different types of cargo.
Keywords
Subjects

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Volume 1, Issue 1 - Serial Number 1
February 2023
Pages 58-69

  • Receive Date 26 August 2022
  • Revise Date 12 October 2022
  • Accept Date 11 December 2022
  • First Publish Date 11 December 2022
  • Publish Date 20 February 2023